Federal Grants for Nonprofits

459 active programs for nonprofits

Nonprofit organizations are eligible for a wide range of US federal funding — from program grants and capacity-building awards to capital grants for facilities and equipment. The programs below accept applications from nonprofits, including 501(c)(3) charities, social-service organizations, faith-based organizations, and community development corporations.

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Research & Innovation Partnerships
Rolling

21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies

Health And Human Services, Department Of, National Institutes Of Health

To provide extramural research support for the Brain Research Through Advancing Innovative Neurotechnologies® (BRAIN) In...

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Health & Biomedical Research
Rolling

21st Century Cures Act - Cancer Moonshot Research Projects

Health And Human Services, Department Of, National Institutes Of Health

To provide support for initiative funding under the 21st Century Cures Act to support cancer research, such as the devel...

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Business Financing & Capital
Rolling

7(j) Technical Assistance

Small Business Administration

The purpose of the program is to provide Business Development Assistance for Small Disadvantaged Businesses. SBA perform...

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Health & Biomedical Research
Rolling

Accelerating Access to Critical Therapies for Amyotrophic Lateral Sclerosis Act

Health And Human Services, Department Of, National Institutes Of Health

Amyotrophic Lateral Sclerosis, or ALS, is a progressive and fatal neurodegenerative disorder, affecting around 30,000 pe...

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Health & Biomedical Research
Rolling

ACL Centers for Independent Living

Health And Human Services, Department Of, Administration For Community Living (acl)

To support a Statewide network of centers for independent living (centers or CILs) and provide financial assistance to c...

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Health & Biomedical Research
Rolling

ACL National Institute on Disability, Independent Living, and Rehabilitation Research

Health And Human Services, Department Of, Administration For Community Living (acl)

To support and coordinate research and its utilization in order to improve the lives of people of all ages with physical...

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Rolling

Acquired Immunodeficiency Syndrome (AIDS) Activity

Health And Human Services, Department Of, Centers For Disease Control And Prevention

To develop and implement HIV prevention programs of public information and education.

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Disaster Resilience
Rolling

Activities to Support State, Tribal, Local and Territorial (STLT) Health Department Response to Public Health or Healthcare Crises

Health And Human Services, Department Of, Centers For Disease Control And Prevention

CDC will strengthen the U.S. public health system’s response to public health or healthcare crises by providing speciali...

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Health & Biomedical Research
Rolling

Addiction Medicine Fellowship Program and Integrated Substance Use Disorder Training Program

Health And Human Services, Department Of, Health Resources And Services Administration

The purpose of the Addiction Medicine Fellowship Program and the Integrated Substance Use Disorder Training Program is t...

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Tribal & Native American Programs
Rolling

Addressing Dementia in Tribal and Urban Indian Communities: Enhancing Sustainable Models of Care

Health And Human Services, Department Of, Indian Health Service

This program is designed to improve clinical care, services, and outcomes for American Indian and Alaska Native (AI/AN)...

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Research & Innovation Partnerships
Rolling

Advanced Manufacturing Technology - Office of the Secretary of Defense (OSD), Manufacturing Technology (ManTech) Program

Dept Of Defense, Immediate Office Of The Secretary Of Defense

Provide Federal financial assistance (FFA) towards the OSW MIIs and OSW's Manufacturing Education and Workforce Developm...

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Rolling

Advanced Nursing Education Workforce Grant Program

Health And Human Services, Department Of, Health Resources And Services Administration

ANEW: The purpose of the Advanced Nursing Education Workforce (ANEW) Program is to increase the number of primary care n...

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Health & Biomedical Research
Rolling

Affordable Care Act (ACA) Personal Responsibility Education Program

Health And Human Services, Department Of, Administration For Children And Families

The Personal Responsibility Education Program (PREP) supports prevention education services for youth ages 10 to 19, to ...

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Rolling

Agricultural Market and Economic Research

Agriculture, Department Of, Usda, Office Of The Chief Economist

To conduct cooperative economic analyses in support of the Office of the Chief Economist's responsibility to advise the ...

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Rolling

AIDS Education and Training Centers (AETC) Program

Health And Human Services, Department Of, Health Resources And Services Administration

The purpose of the Ryan White HIV/AIDS Program (RWHAP) AETC Program is to increase and support a health care workforce c...

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Health & Biomedical Research
Rolling

Air Force Academy Athletic Programs

Dept Of Defense, Dept Of The Air Force

To operate and support the United States Air Force Academy athletic program.

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Research & Innovation Partnerships
Rolling

Air Force Defense Research Sciences Program

Dept Of Defense, Dept Of The Air Force

To maintain technological superiority in the scientific areas relevant to Air Force needs; to prevent technological surp...

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Research & Innovation Partnerships
Rolling

Air Force Medical Research and Development

Dept Of Defense, Dept Of The Air Force

To enhance the health, safety, readiness, and performance of Air Force personnel through applied medical research and ad...

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Regional & Community Development
Rolling

Aircraft Pilots Workforce Development Grant Program

Transportation, Department Of, Federal Aviation Administration

The goal of the Aircraft Pilots Workforce Development Program is to support the creation and delivery of curriculum desi...

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Regional & Community Development
Rolling

Airport Infrastructure Grants

Transportation, Department Of, Federal Aviation Administration

This Assistance Listing Number (ALN) 20.117 was created in August 2025 included in the previous ALN 20.106, please refer...

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Regional & Community Development
Rolling

Airport Terminal Program

Transportation, Department Of, Federal Aviation Administration

This Assistance Listing 20.118 created in August 2025 was included in the previous ALN 20.106, please refer to former AL...

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STEM Research & Education
Rolling

Alternative or Innovative Treatment Technology Research, Demonstration, Training, and Hazardous Substance Research Grants

Environmental Protection Agency

To support grants and cooperative agreements for (1) a program of research, evaluation, testing, development, and demons...

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Health & Biomedical Research
Rolling

Alzheimer’s Disease Initiative: Specialized Supportive Services Project (ADI-SSS) thru Prevention and Public Health Funds (PPHF)

Health And Human Services, Department Of, Administration For Community Living (acl)

The purpose of the Alzheimer’s Disease Initiative: Specialized Supportive Services (ADI-SSS) project is to fill gaps in ...

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Regional & Community Development
Rolling

AmeriCorps Martin Luther King Jr. Day of Service Grants 94.014

Corporation For National And Community Service, Corporation For National And Community Service

The purpose of the Martin Luther King Jr. Day of Service grant funding is to mobilize more Americans to observe the Mart...

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STEM Research & Education
Rolling

AmeriCorps National Service and Civic Engagement Research Competition 94.026

Corporation For National And Community Service, Corporation For National And Community Service

To further achieve its mission, AmeriCorps has a strong belief in the importance of research in order to identify effect...

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STEM Research & Education
Rolling

AmeriCorps Seniors Foster Grandparent Program (FGP) 94.011

Corporation For National And Community Service, Corporation For National And Community Service

The Foster Grandparent Program (FGP) provides grants to qualified agencies and organizations for the dual purpose of eng...

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Regional & Community Development
Rolling

AmeriCorps Seniors Retired and Senior Volunteer Program (RSVP) 94.002

Corporation For National And Community Service, Corporation For National And Community Service

RSVP engages people ages 55 and older to address a wide range of community needs. AmeriCorps Seniors’ volunteers in RSVP...

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Health & Biomedical Research
Rolling

AmeriCorps Seniors Senior Companion Program (SCP) 94.016

Corporation For National And Community Service, Corporation For National And Community Service

The Senior Companion Program (SCP) provides grants to qualified agencies and organizations for the dual purpose of engag...

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Regional & Community Development
Rolling

AmeriCorps September 11th National Day of Service and Remembrance Grants 94.012

Corporation For National And Community Service, Corporation For National And Community Service

The purpose of the September 11th National Day of Service and Remembrance grant funding is to mobilize more Americans to...

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Regional & Community Development
Rolling

AmeriCorps State and National 94.006

Corporation For National And Community Service, Corporation For National And Community Service

AmeriCorps State and National grants are awarded to eligible organizations that identify an unmet need in their communit...

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Regional & Community Development
Rolling

AmeriCorps State Commissions Support Grant

Corporation For National And Community Service, Corporation For National And Community Service

To develop a State plan, to assist States in the application process, and to provide oversight of funded AmeriCorps prog...

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Regional & Community Development
Rolling

AmeriCorps Volunteers In Service to America 94.013

Corporation For National And Community Service, Corporation For National And Community Service

AmeriCorps Volunteers in Service to America (VISTA) is the national service program of AmeriCorps designed specifically ...

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Health & Biomedical Research
Rolling

Area Health Education Centers

Health And Human Services, Department Of, Health Resources And Services Administration

The Area Health Education Centers (AHEC) Program enhances access to high quality health care through academic-community ...

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Research & Innovation Partnerships
Rolling

Arrangements for Interdisciplinary Research Infrastructure

Commerce, Department Of, National Institute Of Standards And Technology

To establish an strengthen new and/or existing centers, consortia, or other arrangements for interdisciplinary research ...

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Arts, Culture & Creative Industries
Rolling

Arts and Artifacts Indemnity

National Endowment For The Arts

To provide for indemnification against loss or damage for eligible art works, artifacts, and objects (1) when borrowed f...

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Rolling

Assistance for Torture Victims

Health And Human Services, Department Of, Administration For Children And Families

The Office of Refugee Resettlement (ORR) funds the Services for Survivors of Torture Program which includes Direct Servi...

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Health & Biomedical Research
Rolling

Assistance Programs for Chronic Disease Prevention and Control

Health And Human Services, Department Of, Centers For Disease Control And Prevention

To work with State health agencies and other public and private nonprofit organizations in planning, developing, integra...

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Rolling

Assisting Specialty Crop Exports

Agriculture, Department Of, Foreign Agricultural Service

ASCE addresses barriers unique to specialty crops exports. It supports projects that advance U.S. specialty crop exports...

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Health & Biomedical Research
Rolling

Assistive Technology Alternative Financing Program

Health And Human Services, Department Of, Administration For Community Living (acl)

The purpose of the Assistive Technology (AT) Alternative Financing Program (AFP) is to support programs that provide for...

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Health & Biomedical Research
Rolling

Autism Collaboration, Accountability, Research, Education, and Support

Health And Human Services, Department Of, Health Resources And Services Administration

This Program supports activities to: provide information and education on autism and other developmental disabilities (D...

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Research & Innovation Partnerships
Rolling

Basic and Applied Scientific Research

Dept Of Defense, Dept Of The Navy

To support and stimulate basic and applied research and technology at educational institutions, non-profits and other re...

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Health & Biomedical Research
Rolling

Basic Center Grant

Health And Human Services, Department Of, Administration For Children And Families

The objectives of the Basic Center Program are to: 1) provide outreach, shelter, crisis intervention and aftercare; 2) r...

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Research & Innovation Partnerships
Rolling

Basic Scientific Research

Dept Of Defense, Dept Of The Army

To support basic research, and enhance fundamental knowledge in the chemical, life, physical, engineering, materials, me...

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Tribal & Native American Programs
Rolling

Behavioral Health Integration Initiative

Health And Human Services, Department Of, Indian Health Service

The objective of the Behavioral Health Integration Initiative (BH2I) program is to improve the physical and mental healt...

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Regional & Community Development
Rolling

Behavioral Traffic Safety Cooperative Research

Transportation, Department Of, National Highway Traffic Safety Administration

The objective is to carry out a cooperative research and evaluation program to research and evaluate priority highway sa...

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Research & Innovation Partnerships
Rolling

Bioengineering, Biomedical Imaging, and Technology Development - Other Research (OR)

Health And Human Services, Department Of, National Institutes Of Health

The Funding Goals of the National Institute of Biomedical Imaging and Bioengineering (NIBIB) are to support the developm...

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Research & Innovation Partnerships
Rolling

Bioengineering, Biomedical Imaging, and Technology Development - Research Centers (RC)

Health And Human Services, Department Of, National Institutes Of Health

The Funding Goals of the National Institute of Biomedical Imaging and Bioengineering (NIBIB) are to support the developm...

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Research & Innovation Partnerships
Rolling

Bioengineering, Biomedical Imaging, and Technology Development - Research Projects

Health And Human Services, Department Of, National Institutes Of Health

The Funding Goals of the National Institute of Biomedical Imaging and Bioengineering (NIBIB) are to support the developm...

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Research & Innovation Partnerships
Rolling

Bioengineering, Biomedical Imaging, and Technology Development - SBIR/STTR

Health And Human Services, Department Of, National Institutes Of Health

The Funding Goals of the National Institute of Biomedical Imaging and Bioengineering (NIBIB) are to support the developm...

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Research & Innovation Partnerships
Rolling

Biomedical Research - Other Research (OR)

Health And Human Services, Department Of, National Institutes Of Health

The National Institute of General Medical Sciences (NIGMS) supports basic research that increases our understanding of b...

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Research & Innovation Partnerships
Rolling

Biomedical Research - Research Centers (RC)

Health And Human Services, Department Of, National Institutes Of Health

The National Institute of General Medical Sciences (NIGMS) supports basic research that increases our understanding of b...

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Research & Innovation Partnerships
Rolling

Biomedical Research - Research Projects (RP)

Health And Human Services, Department Of, National Institutes Of Health

The National Institute of General Medical Sciences (NIGMS) supports basic research that increases our understanding of b...

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Health & Biomedical Research
Rolling

Biomedical Research - Training, Individual (TR)

Health And Human Services, Department Of, National Institutes Of Health

The National Institute of General Medical Sciences (NIGMS) supports basic research that increases our understanding of b...

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Health & Biomedical Research
Rolling

Biomedical Research - Training, Institutional (TI)

Health And Human Services, Department Of, National Institutes Of Health

The National Institute of General Medical Sciences (NIGMS) supports basic research that increases our understanding of b...

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Research & Innovation Partnerships
Rolling

Biomedical Research and Research Training

Health And Human Services, Department Of, National Institutes Of Health

The National Institute of General Medical Sciences (NIGMS) supports basic research that increases our understanding of b...

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Health & Biomedical Research
Rolling

Blood Diseases and Resources Research

Health And Human Services, Department Of, National Institutes Of Health

The National Heart, Lung, and Blood Institute (NHLBI) provides global leadership for a research, training, and education...

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Research & Innovation Partnerships
Rolling

Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative

Health And Human Services, Department Of, National Institutes Of Health

To provide extramural research support for the Brain Research Through Advancing Innovative Neurotechnologies® (BRAIN) In...

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Workforce Development & Training
Rolling

Brookwood-Sago Grant

Labor, Department Of, Mine Safety And Health Administration

To provide mine safety and health training and education programs for workers and mine operators, to better identify, av...

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Rolling

Brownfields Job Training Cooperative Agreements

Environmental Protection Agency

Brownfield sites are real property, the expansion, redevelopment, or reuse of which may be complicated by the presence o...

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Rolling

Brownfields Training, Research, and Technical Assistance Grants and Cooperative Agreements

Environmental Protection Agency

Brownfield sites are real property, the expansion, redevelopment, or reuse of which may be complicated by the presence o...

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Rolling

Capacity Building Assistance (CBA) for High-Impact HIV Prevention

Health And Human Services, Department Of, Centers For Disease Control And Prevention

To reduce morbidity and mortality by preventing cases and complications of HIV and other sexually transmitted diseases b...

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Health & Biomedical Research
Rolling

CARA ACT Comprehensive Addition and Recovery Act of 2016

Health And Human Services, Department Of, Centers For Disease Control And Prevention

Grants awarded through the CARA Act are intended as an enhancement to current or formerly funded Drug-Free Communities (...

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Health & Biomedical Research
Rolling

Cardiovascular Diseases Research

Health And Human Services, Department Of, National Institutes Of Health

The National Heart, Lung, and Blood Institute (NHLBI) provides global leadership for a research, training, and education...

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Health & Biomedical Research
Rolling

CDC Partnership: Strengthening Public Health Laboratories

Health And Human Services, Department Of, Centers For Disease Control And Prevention

The activities under this cooperative agreement are aligned with the following Healthy People 2030 overarching objective...

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Health & Biomedical Research
Rolling

CDC Undergraduate Public Health Scholars Program (CUPS): A Public Health Experience to Expose Undergraduates Interested in Minority Health to Public Health and the Public Health Professions

Health And Human Services, Department Of, Centers For Disease Control And Prevention

The purpose of this funding opportunity is to implement a national summer training program to introduce undergraduate an...

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Health & Biomedical Research
Rolling

Center for Mental Health Services Projects of Regional and National Significance

Health And Human Services, Department Of, Substance Abuse And Mental Health Services Administration

The Center for Mental Health Services (CMHS) projects for regional and national significance support states, tribes and ...

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Rolling

Center for Substance Abuse Prevention Projects of Regional and National Significance

Health And Human Services, Department Of, Substance Abuse And Mental Health Services Administration

The Center for Substance Use Prevention (CSAP) projects for regional and national significance support states, tribes an...

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Rolling

Center for Substance Abuse Treatment Projects of Regional and National Significance

Health And Human Services, Department Of, Substance Abuse And Mental Health Services Administration

The Center for Substance Use Treatment (CSAT) projects for regional and national significance support states, tribes and...

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Health & Biomedical Research
Rolling

Centers of Excellence

Health And Human Services, Department Of, Health Resources And Services Administration

The goal of this program is to assist eligible schools in supporting programs of excellence in health professions educat...

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Health & Biomedical Research
Rolling

Child Health and Human Development Extramural Research

Health And Human Services, Department Of, National Institutes Of Health

The Eunice Kennedy Shriver National Institute of Child Health and Human Development’s mission is to lead research and tr...

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Health & Biomedical Research
Rolling

Child Health and Human Development Extramural Research Projects

Health And Human Services, Department Of, National Institutes Of Health

The Eunice Kennedy Shriver National Institute of Child Health and Human Development’s mission is to lead research and tr...

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Health & Biomedical Research
Rolling

Child Health and Human Development Implementing a Maternal health and PRegnancy Outcomes Vision for Everyone (IMPROVE) Initiative

Health And Human Services, Department Of, National Institutes Of Health

The National Institutes of Health (NIH) launched the IMPROVE initiative in 2019 in response to high rates of pregnancy-r...

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Health & Biomedical Research
Rolling

Child Health and Human Development Other Research

Health And Human Services, Department Of, National Institutes Of Health

The Eunice Kennedy Shriver National Institute of Child Health and Human Development’s mission is to lead research and tr...

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Health & Biomedical Research
Rolling

Child Health and Human Development Research Centers

Health And Human Services, Department Of, National Institutes Of Health

The Eunice Kennedy Shriver National Institute of Child Health and Human Development’s mission is to lead research and tr...

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Health & Biomedical Research
Rolling

Child Health and Human Development Research Training – Individual Awards

Health And Human Services, Department Of, National Institutes Of Health

The Eunice Kennedy Shriver National Institute of Child Health and Human Development’s mission is to lead research and tr...

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Health & Biomedical Research
Rolling

Child Health and Human Development Research Training – Institutional Awards

Health And Human Services, Department Of, National Institutes Of Health

The Eunice Kennedy Shriver National Institute of Child Health and Human Development’s mission is to lead research and tr...

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Rolling

Child Nutrition Discretionary Grants Limited Availability

Agriculture, Department Of, Food And Nutrition Service

National School Lunch Program (NSLP) Equipment Assistance Grants are competitively awarded subgrants to local educationa...

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Health & Biomedical Research
Rolling

Children's Hospitals Graduate Medical Education Payment Program

Health And Human Services, Department Of, Health Resources And Services Administration

The purpose of the CHGME Payment Program is to compensate for the disparity in the level of Federal graduate medical edu...

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Health & Biomedical Research
Rolling

Chronic Diseases: Research, Control, and Prevention

Health And Human Services, Department Of, Centers For Disease Control And Prevention

To assist State and local health agencies, health related organizations, and other public and private organizations in t...

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Defense & National Security
Rolling

Civil Air Patrol Program

Dept Of Defense, Dept Of The Air Force

The purposes of the Civil Air Patrol are: to encourage and aid citizens of the United States in contributing their effor...

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Health & Biomedical Research
Rolling

Closing the Gap Between Standards Development and Implementation

Health And Human Services, Department Of, Immed Office Of The Secretary Of Health And Human Services

To establish a mechanism for ongoing long-term collaborative engagement with Health Level 7 International (HL7) in order...

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Health & Biomedical Research
Rolling

Coal Miners Respiratory Impairment Treatment Clinics and Services

Health And Human Services, Department Of, Health Resources And Services Administration

The Black Lung Clinics Program aims to reduce the morbidity and mortality associated with occupationally-related coal mi...

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Rolling

Cochran Fellowship Program

Agriculture, Department Of, Foreign Agricultural Service

Awards will enhance knowledge and skills to assist eligible countries to develop agricultural systems (which may include...

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Regional & Community Development
Rolling

Commercial Driver's License Program Implementation Grant

Transportation, Department Of, Federal Motor Carrier Safety Administration

Assist States in complying with CDL requirements and dedicate funding to priority activities for research, development a...

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Regional & Community Development
Rolling

Commercial Motor Vehicle Enforcement Training and Support

Transportation, Department Of, Federal Motor Carrier Safety Administration

The objective of the HP- ETS grant program is to train non-federal employees who conduct CMV enforcement activities in a...

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Regional & Community Development
Rolling

Commercial Motor Vehicle Operator Safety Training Grants

Transportation, Department Of, Federal Motor Carrier Safety Administration

Expand the number of commercial driver’s license (CDL) holders possessing enhanced operator safety training to help redu...

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Housing & Community Development
Rolling

Community Compass Technical Assistance and Capacity Building

Housing And Urban Development, Department Of, Assistant Secretary For Policy Development And Research

Community Compass brings together technical assistance funding appropriations from across HUD program offices, including...

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Rolling

Community Development Block Grant- PRICE Competition

Housing And Urban Development, Department Of, Assistant Secretary For Community Planning And Development

The Community Development Block Grant - Preservation and Reinvestment Initiative for Community Enhancement (CDBG-PRICE) ...

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Housing & Community Development
Rolling

Community Development Block Grants/Special Purpose Grants/Insular Areas

Housing And Urban Development, Department Of, Assistant Secretary For Community Planning And Development

To provide community development assistance to the Pacific Islands of American Samoa, Guam, the Northern Mariana Islands...

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Housing & Community Development
Rolling

Community Development Block Grants/State's program and Non-Entitlement Grants in Hawaii

Housing And Urban Development, Department Of, Assistant Secretary For Community Planning And Development

The primary objective of this program is the development of viable urban communities by providing decent housing, a suit...

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Regional & Community Development
Rolling

Community Development Financial Institutions Bond Guarantee Program

Treasury, Department Of The, Community Development Financial Institutions

To support community development lending and investment by providing a source of long-term capital to certified Communit...

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Business Financing & Capital
Rolling

Community Navigator Pilot Program

Small Business Administration

Per the American Rescue Plan, the SBA is authorized to create and administer a $100 million competitive grant program t...

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Tribal & Native American Programs
Rolling

Community Opioid Intervention Prevention Program

Health And Human Services, Department Of, Indian Health Service

The Indian Health Service Behavioral Health Programs consists of several funding programs designed to help Tribes, Triba...

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Workforce Development & Training
Rolling

Community Project Funding/Congressionally Directed Spending

Labor, Department Of, Employment And Training Administration

The goal is to fund projects in the amounts specified in the table titled “Community Project Funding/Congressional Direc...

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Regional & Community Development
Rolling

Community Services Block Grant

Health And Human Services, Department Of, Administration For Children And Families

The objectives of the Community Services Block Grant (CSBG) are to provide assistance to states and local communities, w...

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Housing & Community Development
Rolling

Community Services Block Grant Discretionary Awards

Health And Human Services, Department Of, Administration For Children And Families

CED and RCD are two funding opportunities in this program with a focus on development of communities with low income. CE...

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Health & Biomedical Research
Rolling

Complementary and Integrative Health - Other Research

Health And Human Services, Department Of, National Institutes Of Health

NCCIH is the lead Federal agency for scientific research on the fundamental science, usefulness, and safety of complemen...

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Health & Biomedical Research
Rolling

Complementary and Integrative Health - Research Centers

Health And Human Services, Department Of, National Institutes Of Health

NCCIH is the lead Federal agency for scientific research on the fundamental science, usefulness, and safety of complemen...

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Health & Biomedical Research
Rolling

Complementary and Integrative Health - Research Projects

Health And Human Services, Department Of, National Institutes Of Health

NCCIH is the lead Federal agency for scientific research on the fundamental science, usefulness, and safety of complemen...

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Health & Biomedical Research
Rolling

Complementary and Integrative Health - SBIR/STTR

Health And Human Services, Department Of, National Institutes Of Health

NCCIH is the lead Federal agency for scientific research on the fundamental science, usefulness, and safety of complemen...

Other applicant types