21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies
Department Of Health And Human Services, National Institutes Of Health
To provide extramural research support for the Brain Research Through Advancing Innovative Neurotechnologies® (BRAIN) Initiative’s aim of revolutionizing our understanding of the brain and its function in unprecedented detail. The NIH BRAIN Initiative’s focus is foundational development of new technologies and tools to map, monitor, and modulate brain circuits in model systems and humans – toward the ultimate goal of treating and curing human brain disorders. BRAIN Initiative research adheres to
Jargon-free version
Helps researchers develop new technologies to better understand the brain and treat brain disorders. This initiative supports innovative projects that aim to improve treatments for conditions like depression and Parkinson's disease.
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What Is This Program?
What Benefits Are Offered?
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📋What Are the Application Steps & Timeline?
- 📝Steps to Apply
- Identify research objectives
- Prepare application materials
- Submit application through the designated portal
- Await review and feedback
- Receive funding decision
- 🌐Application Portal
- https://www.braininitiative.nih.gov/
- 📤Submission Method
- online
- 🔄Intake Type
- fixed-deadline
📄What Documents Are Required?
- ✅Required Documents
- SF-424 (Application for Federal Assistance)
- SF-424A (Budget Information - Non-Construction)
- SF-424B (Assurances)
- Project Narrative
- Budget Narrative
- 📎Optional Documents
- indirect cost rate agreement
- IRB approval letter
- environmental review
- 📐Format Requirements
- PDF only, max 10MB
- 📥Templates Available
- ✉️Supporting Letters
- Letters of support/reference are required.
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💰What Expenses Are Eligible?
- 🧾Eligible Expenses
- Research costs
- Development of innovative technologies
- Clinical trials
- Data analysis
- Personnel costs
- 🚫Ineligible Expenses
- Costs unrelated to brain research
- Administrative costs not directly related to projects
- 📏Expense Caps
- Indirect costs limited to de minimis 10% MTDC
- 💳Payment Model
- mixed
- ⏪Retroactive Expenses Eligible
- No
🤝Is Matching Funding Required?
📊What Are the Reporting Requirements?
- 🗓️Reporting Frequency
- annual
- 📑Reporting Requirements
- progress and achievements report
- 🔍Audit Requirements
- OMB Uniform Guidance Single Audit if the recipient expends $750,000 or more in federal awards in a fiscal year
- 📢Branding Requirements
- Acknowledgment of federal funding
- 🗄️Record Retention Period
- 3 years post-final-report
How Do I Apply?
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FAQFrequently Asked Questions
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