21st Century Cures Act - Cancer Moonshot Research Projects

Department Of Health And Human Services, National Institutes Of Health

To provide support for initiative funding under the 21st Century Cures Act to support cancer research, such as the development of cancer vaccines, the development of more sensitive diagnostic tests for cancer, immunotherapy for adults and children, the development of combination therapies, deeper understanding of tumor evolution, the development of implementation science, as well as research that is inherently higher risk, but that has the potential to transform cancer therapy, and research that

Jargon-free version

Helps researchers develop new cancer treatments and diagnostic tests. Supports innovative projects that could transform cancer therapy.

Quick Facts

Funding
Contact for details
Deadline
Rolling
Status
Rolling Intake
Category
Health & Biomedical Research
Organization
Department Of Health And Human Services, National Institutes Of Health

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What Is This Program?

To provide support for initiative funding under the 21st Century Cures Act to support cancer research, such as the development of cancer vaccines, the development of more sensitive diagnostic tests for cancer, immunotherapy for adults and children, the development of combination therapies, deeper understanding of tumor evolution, the development of implementation science, as well as research that is inherently higher risk, but that has the potential to transform cancer therapy, and research that seeks to address major challenges related to cancer.

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๐Ÿ† Detailed Application Guide

๐Ÿ“‹What Are the Application Steps & Timeline?

๐Ÿ“Steps to Apply
  • Review the funding opportunity announcement
  • Prepare the application materials
  • Submit the application through the designated portal
๐ŸŒApplication Portal
https://sam.gov/fal/a16555ccd4894fc58ff8997702f6175f/view
๐Ÿ“คSubmission Method
online
๐Ÿ”„Intake Type
fixed-deadline

๐Ÿ“„What Documents Are Required?

โœ…Required Documents
  • SF-424 (Application for Federal Assistance)
  • SF-424A (Budget Information - Non-Construction)
  • SF-424B (Assurances)
  • Project Narrative
  • Budget Narrative
  • indirect cost rate agreement
  • IRB approval letter
  • environmental review
๐Ÿ“Format Requirements
PDF only, max 10MB
โœ‰๏ธSupporting Letters
Letters of support are required.

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๐Ÿ’ฐWhat Expenses Are Eligible?

๐ŸงพEligible Expenses
  • research costs
  • personnel expenses
  • supplies
  • equipment
  • contractual services
๐ŸšซIneligible Expenses
  • entertainment costs
  • fines and penalties
  • alcoholic beverages
๐Ÿ“Expense Caps
Indirect costs limited to de minimis 10% MTDC
๐Ÿ’ณPayment Model
reimbursement
โชRetroactive Expenses Eligible
No

๐ŸคIs Matching Funding Required?

๐Ÿ“ŠWhat Are the Reporting Requirements?

๐Ÿ—“๏ธReporting Frequency
annual
๐Ÿ“‘Reporting Requirements
  • SF-425 Federal Financial Report
  • performance progress report
๐Ÿ”Audit Requirements
OMB Uniform Guidance Single Audit if the recipient expends $750,000 or more in federal awards.
๐Ÿ“ขBranding Requirements
Acknowledgment of federal funding is required.
๐Ÿ—„๏ธRecord Retention Period
3 years post-final-report

How Do I Apply?

scott.chen@nih.gov
240-276-6038

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FAQFrequently Asked Questions

Visit the program page for detailed eligibility requirements.

Contact the program administrator for funding details.

This program accepts applications on a rolling basis.

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