National Center for Advancing Translational Sciences - Research Projects

Department Of Health And Human Services, National Institutes Of Health

The National Center for Advancing Translational Sciences' (NCATS') mission is to turn research observations into health solutions through translational science. We work to develop or enhance the development, testing, and implementation of diagnostics and therapeutics for a wide range of diseases and conditions. Key approaches include understanding what’s similar across diseases to spur multiple treatments at a time, developing models that better predict a person’s reaction to treatment, enhancin

Jargon-free version

Helps small businesses develop and commercialize new health technologies. Provides funding and support for research that leads to faster treatments and cures.

Quick Facts

Funding
$1,879,001 - $5,694,461
Deadline
Rolling
Status
Rolling Intake
Category
Research & Innovation Partnerships
Organization
Department Of Health And Human Services, National Institutes Of Health

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What Is This Program?

The National Center for Advancing Translational Sciences (NCATS) at the National Institutes of Health (NIH) was established to transform the translational science process so that new treatments and cures for disease can be delivered to patients faster. NCATS strives to develop innovations to reduce, remove or bypass costly and time-consuming bottlenecks in the translational research pipeline in an effort to speed the delivery of new drugs, diagnostics and medical devices to patients.

What Benefits Are Offered?

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🏆 Detailed Application Guide

📋What Are the Application Steps & Timeline?

📝Steps to Apply
  • Explore funding opportunities
  • Prepare grant application
  • Submit application through the online portal
  • Await peer review and funding decision
🌐Application Portal
https://ncats.nih.gov/funding
📤Submission Method
online
📅Key Dates
05/12/2026Posting Date
06/15/2028Expiration Date
🔄Intake Type
fixed-deadline

📄What Documents Are Required?

Required Documents
  • SF-424 (Application for Federal Assistance)
  • SF-424A (Budget Information - Non-Construction)
  • SF-424B (Assurances)
  • Project Narrative
  • Budget Narrative
  • indirect cost rate agreement
  • IRB approval letter
  • environmental review
📐Format Requirements
PDF only, max 10MB
✉️Supporting Letters
Letters of support/reference may be required.

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💰What Expenses Are Eligible?

🧾Eligible Expenses
  • research activities
  • clinical trials
  • drug discovery and development
  • training and education
  • preclinical and clinical research tools

🤝Is Matching Funding Required?

📊What Are the Reporting Requirements?

🗓️Reporting Frequency
annual
📑Reporting Requirements
  • SF-425 Federal Financial Report
  • performance progress report
🔍Audit Requirements
OMB Uniform Guidance Single Audit if the recipient expends $750,000 or more in federal awards in a fiscal year
📢Branding Requirements
Acknowledgment of federal funding is required
🗄️Record Retention Period
3 years post-final-report

How Do I Apply?

NCATSExtramuralInfo@mail.nih.gov
(301) 594-8966

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FAQFrequently Asked Questions

Visit the program page for detailed eligibility requirements.

This program offers funding up to $5,694,461 (minimum $1,879,001).

This program accepts applications on a rolling basis.

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