National Center for Advancing Translational Sciences - Research Centers
Department Of Health And Human Services, National Institutes Of Health
The National Center for Advancing Translational Sciences' (NCATS') mission is to turn research observations into health solutions through translational science. We work to develop or enhance the development, testing, and implementation of diagnostics and therapeutics for a wide range of diseases and conditions. Key approaches include understanding what’s similar across diseases to spur multiple treatments at a time, developing models that better predict a person’s reaction to treatment, enhancin
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Helps small businesses develop and commercialize new health technologies. Provides funding and support to speed up research and bring solutions to patients faster.
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What Is This Program?
What Benefits Are Offered?
Funding and technical assistance for a range of research and development activities in translational science, including small business innovation, clinical trials, individual fellowships, scientific conference support, and prize competitions, all aimed at speeding health solutions and commercialization.
Who Is Eligible?
Business Size: small
Industries: biotechnology, life sciences, health tech, research and development
Region: United States
Other Criteria: small businesses, research organizations, researchers, early-stage companies, entrepreneurial researchers, developing and commercializing new translational technologies, addressing research priorities in the translational space, projects relevant to public health and NCATS mission, high-quality national and international meetings (for conference grants)
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Browse Partner Directory🏆 Detailed Application Guide
📋What Are the Application Steps & Timeline?
- 📝Steps to Apply
- Explore funding opportunities
- Prepare grant application
- Submit application via online portal
- Await peer review results
- Receive funding decision
- 🌐Application Portal
- https://ncats.nih.gov/funding/open-funding-opportunities
- 📤Submission Method
- online
- 📅Key Dates
- 05/12/2026Posting Date for RFA-OD-27-00506/15/2028Expiration Date for RFA-OD-27-00505/11/2026Posting Date for RFA-OD-27-00406/15/2028Expiration Date for RFA-OD-27-004
- 🔄Intake Type
- fixed-deadline
📄What Documents Are Required?
- ✅Required Documents
- SF-424 (Application for Federal Assistance)
- SF-424A (Budget Information - Non-Construction)
- SF-424B (Assurances)
- Project Narrative
- Budget Narrative
- indirect cost rate agreement
- IRB approval letter
- environmental review
- 📐Format Requirements
- PDF only, max 10MB
- ✉️Supporting Letters
- Letters of support/reference are required.
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💰What Expenses Are Eligible?
- 🧾Eligible Expenses
- research activities
- clinical trials
- drug discovery and development
- training and education programs
- 💳Payment Model
- mixed
🤝Is Matching Funding Required?
📊What Are the Reporting Requirements?
- 🗓️Reporting Frequency
- annual
- 📑Reporting Requirements
- SF-425 Federal Financial Report
- performance progress report
- 🔍Audit Requirements
- OMB Uniform Guidance Single Audit if the recipient expends $750,000 or more in federal awards in a fiscal year
- 📢Branding Requirements
- Acknowledgment of federal funding is required.
- 🗄️Record Retention Period
- 3 years post-final-report
How Do I Apply?
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FAQFrequently Asked Questions
This program is available to small businesses in biotechnology, life sciences, health tech industries located in United States.
Contact the program administrator for funding details.
This program accepts applications on a rolling basis.
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