National Center for Advancing Translational Sciences - Cures Acceleration Network
Department Of Health And Human Services, National Institutes Of Health
The National Center for Advancing Translational Sciences' (NCATS') mission is to turn research observations into health solutions through translational science. We work to develop or enhance the development, testing, and implementation of diagnostics and therapeutics for a wide range of diseases and conditions. Key approaches include understanding what’s similar across diseases to spur multiple treatments at a time, developing models that better predict a person’s reaction to treatment, enhancin
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Helps small businesses develop and commercialize new health technologies. Provides funding and resources to speed up the creation of important medical treatments.
Quick Facts
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What Is This Program?
What Benefits Are Offered?
Provides a wide array of funding opportunities (including grants, cooperative agreements, fellowships), technical assistance, training, and resources to advance translational science, accelerate health solutions, and support the development and commercialization of new technologies by small businesses and research organizations.
Who Is Eligible?
Business Size: small
Industries: biotechnology, life sciences, medical devices, healthcare IT, research and development
Region: United States
Other Criteria: research organizations, researchers, early-stage companies, entrepreneurial researchers, projects with commercialization potential, projects with public benefit, innovative ideas, relevant to public health and NCATS mission, NIH-funded entities/projects
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Browse Partner Directory🏆 Detailed Application Guide
📋What Are the Application Steps & Timeline?
- 📝Steps to Apply
- Explore funding opportunities
- Prepare grant application
- Submit application for review
- Undergo peer review process
- Receive funding decision
- 🌐Application Portal
- https://ncats.nih.gov/funding
- 📤Submission Method
- online
- 📅Key Dates
- 05/12/2026Posting Date for RFA-OD-27-00505/11/2026Posting Date for RFA-OD-27-004
- 🔄Intake Type
- fixed-deadline
📄What Documents Are Required?
- ✅Required Documents
- SF-424 (Application for Federal Assistance)
- SF-424A (Budget Information - Non-Construction)
- SF-424B (Assurances)
- Project Narrative
- Budget Narrative
- indirect cost rate agreement
- IRB approval letter
- environmental review
- 📐Format Requirements
- PDF only, max 10MB
- ✉️Supporting Letters
- Letters of support/reference may be required.
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💰What Expenses Are Eligible?
- 🧾Eligible Expenses
- research activities
- clinical trials
- drug discovery and development
- training and education
- in-kind support services
- 💳Payment Model
- mixed
🤝Is Matching Funding Required?
📊What Are the Reporting Requirements?
- 🗓️Reporting Frequency
- annual
- 📑Reporting Requirements
- SF-425 Federal Financial Report
- performance progress report
- 🔍Audit Requirements
- OMB Uniform Guidance Single Audit if the recipient expends $750,000 or more in federal awards.
- 📢Branding Requirements
- Acknowledgment of federal funding is required.
- 🗄️Record Retention Period
- 3 years post-final-report
How Do I Apply?
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FAQFrequently Asked Questions
This program is available to small businesses in biotechnology, life sciences, medical devices industries located in United States.
This program offers funding up to $3,038,500 (minimum $3,038,500).
This program accepts applications on a rolling basis.
Choose your tier
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5 columns per program
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24 columns per program
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- Everything in Basic, plus 23 more columns
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- Everything in Pro, plus 25 more deep-extracted columns
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- Eligible / ineligible expenses, expense caps, payment model
- Matching ratios, eligible sources, stacking rules
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- Plain-English 1-2 sentence rewrite of every program
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