National Center for Advancing Translational Sciences - Clinical and Translational Science Awards

Department Of Health And Human Services, National Institutes Of Health

The National Center for Advancing Translational Sciences' (NCATS') mission is to turn research observations into health solutions through translational science. We work to develop or enhance the development, testing, and implementation of diagnostics and therapeutics for a wide range of diseases and conditions. Key approaches include understanding whatโ€™s similar across diseases to spur multiple treatments at a time, developing models that better predict a personโ€™s reaction to treatment, enhancin

Jargon-free version

Helps medical institutions improve healthcare by speeding up research discoveries into practical treatments. Provides resources, training, and partnerships to enhance clinical research efforts.

Quick Facts

Funding
$2,100,000 - $2,100,000
Deadline
Rolling
Status
Rolling Intake
Category
Research & Innovation Partnerships
Organization
Department Of Health And Human Services, National Institutes Of Health

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What Is This Program?

Under NCATSโ€™ leadership, the Clinical and Translational Science Awards (CTSA) Program supports a national network of medical institutions that speeds the translation of research discoveries into improved care. Currently, more than 60 leading medical institutions across the nation receive CTSA Program funding. The institutions offer expertise, resources and partnerships at the national and local levels to improve the health of individuals and communities. The CTSA Program also nurtures the field of translational science through education, training and career support at all levels. The CTSA Program Goals are to: - Advance clinical and translational science: develop, demonstrate and disseminate scientific and operational innovations that improve the efficiency and effectiveness of clinical translation from identification to first-in-human studies to medical practice implementation to community health dissemination. - Promote partnerships and collaborations to facilitate and accelerate translational research projects locally, regionally and nationally. - Create, provide, and disseminate innovative research programs and partnerships across institutions and communities to address health needs of their populations and deliver the benefits of translational science to all. - Create and implement scientific and operational innovations that increase the quality, safety, efficiency, effectiveness and informativeness of clinical research. - Provide a national resource for the rapid response to urgent public health needs. - Create, provide and disseminate clinical and translational science training programs for clinical research professionals of all disciplines on the research team. - Create, provide and disseminate clinical and translational science training and career support programs for translational scientists. - Foster the development of the emerging field of translational science.

What Benefits Are Offered?

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NCATS offers funding, technical assistance, and collaboration opportunities, primarily through its SBIR/STTR programs and general research grants. These benefits support researchers and small businesses in advancing translational science, developing health technologies, and commercializing innovative solutions that address public health challenges. Conference grants and prize competitions are also available.

Who Is Eligible?

Business Size: small

Industries: life sciences, biotechnology, medical devices, healthcare technology, research & development

Region: United States

Other Criteria: early-stage companies, research organizations, researchers, engaged in research and development with commercialization potential, projects relevant to translational science and public health, developing clinical technology, instruments, and devices

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๐Ÿ† Detailed Application Guide

๐Ÿ“‹What Are the Application Steps & Timeline?

๐Ÿ“Steps to Apply
  • Identify funding opportunity
  • Prepare application materials
  • Submit application via online portal
  • Await peer review results
  • Receive funding decision
๐ŸŒApplication Portal
https://ncats.nih.gov/funding
๐Ÿ“คSubmission Method
online
๐Ÿ“…Key Dates
05/12/2026Posting Date for RFA-OD-27-005
06/15/2028Expiration Date for RFA-OD-27-005
05/11/2026Posting Date for RFA-OD-27-004
06/15/2028Expiration Date for RFA-OD-27-004
๐Ÿ”„Intake Type
fixed-deadline

๐Ÿ“„What Documents Are Required?

โœ…Required Documents
  • SF-424 (Application for Federal Assistance)
  • SF-424A (Budget Information - Non-Construction)
  • SF-424B (Assurances)
  • Project Narrative
  • Budget Narrative
  • indirect cost rate agreement
  • IRB approval letter
  • environmental review
๐Ÿ“Format Requirements
PDF only, max 10MB
โœ‰๏ธSupporting Letters
Letters of support/reference may be required.

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๐Ÿ’ฐWhat Expenses Are Eligible?

๐ŸงพEligible Expenses
  • research activities
  • clinical trials
  • training and education
  • development of health solutions
๐Ÿ’ณPayment Model
mixed

๐ŸคIs Matching Funding Required?

๐Ÿ“ŠWhat Are the Reporting Requirements?

๐Ÿ—“๏ธReporting Frequency
annual
๐Ÿ“‘Reporting Requirements
  • SF-425 Federal Financial Report
  • performance progress report
๐Ÿ”Audit Requirements
OMB Uniform Guidance Single Audit if the recipient expends $750,000 or more in federal awards in a fiscal year.
๐Ÿ“ขBranding Requirements
Acknowledgment of federal funding is required in publications and presentations.
๐Ÿ—„๏ธRecord Retention Period
3 years post-final-report

How Do I Apply?

NCATSExtramuralInfo@mail.nih.gov
301-594-8966

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FAQFrequently Asked Questions

This program is available to small businesses in life sciences, biotechnology, medical devices industries located in United States.

This program offers funding up to $2,100,000 (minimum $2,100,000).

This program accepts applications on a rolling basis.

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