National Center for Advancing Translational Sciences - Clinical and Translational Science Awards
Department Of Health And Human Services, National Institutes Of Health
The National Center for Advancing Translational Sciences' (NCATS') mission is to turn research observations into health solutions through translational science. We work to develop or enhance the development, testing, and implementation of diagnostics and therapeutics for a wide range of diseases and conditions. Key approaches include understanding whatโs similar across diseases to spur multiple treatments at a time, developing models that better predict a personโs reaction to treatment, enhancin
Jargon-free version
Helps medical institutions improve healthcare by speeding up research discoveries into practical treatments. Provides resources, training, and partnerships to enhance clinical research efforts.
Quick Facts
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What Is This Program?
What Benefits Are Offered?
NCATS offers funding, technical assistance, and collaboration opportunities, primarily through its SBIR/STTR programs and general research grants. These benefits support researchers and small businesses in advancing translational science, developing health technologies, and commercializing innovative solutions that address public health challenges. Conference grants and prize competitions are also available.
Who Is Eligible?
Business Size: small
Industries: life sciences, biotechnology, medical devices, healthcare technology, research & development
Region: United States
Other Criteria: early-stage companies, research organizations, researchers, engaged in research and development with commercialization potential, projects relevant to translational science and public health, developing clinical technology, instruments, and devices
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Browse Partner Directory๐ Detailed Application Guide
๐What Are the Application Steps & Timeline?
- ๐Steps to Apply
- Identify funding opportunity
- Prepare application materials
- Submit application via online portal
- Await peer review results
- Receive funding decision
- ๐Application Portal
- https://ncats.nih.gov/funding
- ๐คSubmission Method
- online
- ๐ Key Dates
- 05/12/2026Posting Date for RFA-OD-27-00506/15/2028Expiration Date for RFA-OD-27-00505/11/2026Posting Date for RFA-OD-27-00406/15/2028Expiration Date for RFA-OD-27-004
- ๐Intake Type
- fixed-deadline
๐What Documents Are Required?
- โ Required Documents
- SF-424 (Application for Federal Assistance)
- SF-424A (Budget Information - Non-Construction)
- SF-424B (Assurances)
- Project Narrative
- Budget Narrative
- indirect cost rate agreement
- IRB approval letter
- environmental review
- ๐Format Requirements
- PDF only, max 10MB
- โ๏ธSupporting Letters
- Letters of support/reference may be required.
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๐ฐWhat Expenses Are Eligible?
- ๐งพEligible Expenses
- research activities
- clinical trials
- training and education
- development of health solutions
- ๐ณPayment Model
- mixed
๐คIs Matching Funding Required?
๐What Are the Reporting Requirements?
- ๐๏ธReporting Frequency
- annual
- ๐Reporting Requirements
- SF-425 Federal Financial Report
- performance progress report
- ๐Audit Requirements
- OMB Uniform Guidance Single Audit if the recipient expends $750,000 or more in federal awards in a fiscal year.
- ๐ขBranding Requirements
- Acknowledgment of federal funding is required in publications and presentations.
- ๐๏ธRecord Retention Period
- 3 years post-final-report
How Do I Apply?
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FAQFrequently Asked Questions
This program is available to small businesses in life sciences, biotechnology, medical devices industries located in United States.
This program offers funding up to $2,100,000 (minimum $2,100,000).
This program accepts applications on a rolling basis.
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