Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative

Department Of Health And Human Services, National Institutes Of Health

To provide extramural research support for the Brain Research Through Advancing Innovative Neurotechnologies® (BRAIN) Initiative’s aim of revolutionizing our understanding of the brain and its function in unprecedented detail. The NIH BRAIN Initiative’s focus is foundational development of new technologies and tools to map, monitor, and modulate brain circuits in model systems and humans – toward the ultimate goal of treating and curing human brain disorders. BRAIN Initiative research adheres to

Jargon-free version

Helps researchers develop new technologies to better understand the brain and treat brain disorders. This initiative supports innovative projects that advance neuroscience and improve patient care.

Quick Facts

Funding
Contact for details
Deadline
Rolling
Status
Rolling Intake
Category
Research & Innovation Partnerships
Organization
Department Of Health And Human Services, National Institutes Of Health

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What Is This Program?

The Brain Research through Advancing Innovative Neurotechnologies® (BRAIN) Initiative aims to accelerate the development and application of innovative neurotechnologies, enabling researchers to produce a new dynamic picture of the brain that reveals how individual cells and complex neural circuits interact in both time and space. It is expected that these advances will ultimately lead to new ways to treat and prevent brain disorders.

What Benefits Are Offered?

funding

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🏆 Detailed Application Guide

📋What Are the Application Steps & Timeline?

📝Steps to Apply
  • Identify research objectives
  • Prepare application materials
  • Submit application through the designated portal
  • Await review and funding decision
🌐Application Portal
https://braininitiative.nih.gov/
📤Submission Method
online
🔄Intake Type
rolling

📄What Documents Are Required?

Required Documents
  • SF-424 (Application for Federal Assistance)
  • SF-424A (Budget Information - Non-Construction)
  • SF-424B (Assurances)
  • Project Narrative
  • Budget Narrative
  • indirect cost rate agreement
  • IRB approval letter
  • environmental review
📐Format Requirements
PDF only, max 10MB
✉️Supporting Letters
Letters of support are required from collaborators or partners involved in the project.

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💰What Expenses Are Eligible?

🧾Eligible Expenses
  • Research costs
  • Development of innovative technologies
  • Clinical trials
  • Data analysis tools
  • Neuroscience research
🚫Ineligible Expenses
  • Costs unrelated to neuroscience research
  • Costs for non-research activities
📏Expense Caps
Indirect costs limited to de minimis 10% MTDC
💳Payment Model
mixed
Retroactive Expenses Eligible
No

🤝Is Matching Funding Required?

🔀Matching Required
No
🏦Eligible Matching Sources
  • cash
  • in-kind
📚Stacking Rules
Yes, can combine with other government funding.
🛡️Proof of Matching Required
Documentation of matching funds is required.

📊What Are the Reporting Requirements?

🗓️Reporting Frequency
annual
📑Reporting Requirements
  • progress and achievements report
🔍Audit Requirements
OMB Uniform Guidance Single Audit if the recipient expends $750,000 or more in federal awards in a fiscal year
📢Branding Requirements
Acknowledge federal funding and use agency logos as required
🗄️Record Retention Period
3 years post-final-report

How Do I Apply?

crystal.lantz@nih.gov
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