ADVANCED RESEARCH PROJECTS AGENCY for HEALTH (ARPA-H)

Department Of Health And Human Services, National Institutes Of Health

The purpose of this program is to coordinate the acceleration of biomedical and health breakthroughs to deliver transformative, sustainable, and equitable health solutions for everyone by โ€“ (A) facilitating collaboration between Advance Research Projects Agency for Health and other Federal agencies, relevant industries, academia, and other persons, with respect to advance high-potential, high impact biomedical and health research that cannot be readily accomplished through traditional research a

Jargon-free version

Helps small businesses develop innovative health technologies that can improve patient care. Provides funding and support to turn groundbreaking ideas into real solutions.

Quick Facts

Funding
$7,600,000 - $7,600,000
Deadline
Rolling
Status
Rolling Intake
Category
Research & Innovation Partnerships
Organization
Department Of Health And Human Services, National Institutes Of Health

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What Is This Program?

ARPA-H shall achieve goals stated above by supporting: Discovery, identification, and promotion of revolutionary advancements in science; Translation of scientific discoveries into transformative health technologies with potential application for biomedical science and medicine; Creation of platform capabilities that draw on multiple disciplines; Delivery of proofs of concept that demonstrate meaningful advances with potential clinical application; Development of new capabilities and methods to identify potential targets and technological strategies for early disease detection and intervention, such as advanced computational tools and predictive models; and Acceleration of transformational health technological advances in areas with limited technical certainty.

What Benefits Are Offered?

funding

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๐Ÿ† Detailed Application Guide

๐Ÿ“‹What Are the Application Steps & Timeline?

๐Ÿ“Steps to Apply
  • Identify a broad research focus area or specific research program
  • Submit a Solution Summary
  • Receive feedback from ARPA-H
  • Submit a full proposal after receiving feedback
  • Negotiate terms and conditions if selected
  • Execute tasks and receive payment per agreement milestones
  • Complete and close out the agreement
๐ŸŒApplication Portal
https://solutions.arpa-h.gov
๐Ÿ“คSubmission Method
online
๐Ÿ“…Key Dates
July 10, 2026Solution Summary Due
September 9, 2026Technical Oral Presentation Due
๐Ÿ”„Intake Type
rolling

๐Ÿ“„What Documents Are Required?

โœ…Required Documents
  • SF-424 (Application for Federal Assistance)
  • SF-424A (Budget Information - Non-Construction)
  • SF-424B (Assurances)
  • Project Narrative
  • Budget Narrative
  • indirect cost rate agreement
  • IRB approval letter
  • environmental review
๐Ÿ“Format Requirements
PDF only, max 10MB
โœ‰๏ธSupporting Letters
Letters of support/reference are not explicitly required but may enhance proposals.

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๐Ÿ’ฐWhat Expenses Are Eligible?

๐ŸงพEligible Expenses
  • research and development costs
  • project execution costs
  • milestone-related expenses
๐ŸšซIneligible Expenses
  • costs not directly related to project execution
  • general administrative costs not specified in agreement
๐Ÿ“Expense Caps
Indirect costs limited to de minimis 10% MTDC
๐Ÿ’ณPayment Model
milestone
โชRetroactive Expenses Eligible
No

๐ŸคIs Matching Funding Required?

๐Ÿ“ŠWhat Are the Reporting Requirements?

๐Ÿ—“๏ธReporting Frequency
annual
๐Ÿ“‘Reporting Requirements
  • performance progress report
๐Ÿ”Audit Requirements
OMB Uniform Guidance Single Audit if the recipient expends $750,000 or more in federal awards
๐Ÿ“ขBranding Requirements
acknowledgment of federal funding
๐Ÿ—„๏ธRecord Retention Period
3 years post-final-report

How Do I Apply?

elizabeth.fuller@arpa-h.gov
2407531172

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FAQFrequently Asked Questions

Visit the program page for detailed eligibility requirements.

This program offers funding up to $7,600,000 (minimum $7,600,000).

This program accepts applications on a rolling basis.

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